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Formulation of a Thermosensitive Imaging Hydrogel for Topical Application and Rapid Visualization of Tumor Margins in the Surgical Cavity

SIMPLE SUMMARY: We have developed a formulation for an innovative, quenched, cathepsin-targeted, fluorescent molecular probe to enhance resection quality for several solid-tumor cancers. Unlike other formulations for imaging probes or tracers in development and entering the clinic, which require sys...

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Detalles Bibliográficos
Autores principales: Walker, Ethan, Linders, Daan G. J., Abenojar, Eric, Wang, Xinning, Hazelbag, Hans Marten, Straver, Marieke E., Bijlstra, Okker D., March, Taryn L., Vahrmeijer, Alexander L., Exner, Agata, Bogyo, Matthew, Basilion, James P., Straight, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323389/
https://www.ncbi.nlm.nih.gov/pubmed/35884520
http://dx.doi.org/10.3390/cancers14143459