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Combination of E- and NS1-Derived DNA Vaccines: The Immune Response and Protection Elicited in Mice against DENV2

The occurrence of dengue disease has increased radically in recent decades. Previously, we constructed the pE1D2 and pcTPANS1 DNA vaccines encoding the DENV2 envelope (E) and non-structural 1 (NS1) proteins, respectively. To decrease the number of plasmids in a tetravalent candidate vaccine, we cons...

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Detalles Bibliográficos
Autores principales: Pinto, Paolla Beatriz A., Barros, Tamiris A. C., Lima, Lauro M., Pacheco, Agatha R., Assis, Maysa L., Pereira, Bernardo A. S., Gonçalves, Antônio J. S., Azevedo, Adriana S., Neves-Ferreira, Ana Gisele C., Costa, Simone M., Alves, Ada M. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323404/
https://www.ncbi.nlm.nih.gov/pubmed/35891431
http://dx.doi.org/10.3390/v14071452