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Oxygenating Biocatalysts for Hydroxyl Functionalisation in Drug Discovery and Development

C−H oxyfunctionalisation remains a distinct challenge for synthetic organic chemists. Oxygenases and peroxygenases (grouped here as “oxygenating biocatalysts”) catalyse the oxidation of a substrate with molecular oxygen or hydrogen peroxide as oxidant. The application of oxygenating biocatalysts in...

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Detalles Bibliográficos
Autores principales: Charlton, Sacha N., Hayes, Martin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323455/
https://www.ncbi.nlm.nih.gov/pubmed/35385205
http://dx.doi.org/10.1002/cmdc.202200115