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A Computational–Experimental Investigation of the Molecular Mechanism of Interleukin-6-Piperine Interaction

Herein, we elucidate the biophysical aspects of the interaction of an important protein, Interleukin-6 (IL6), which is involved in cytokine storm syndrome, with a natural product with anti-inflammatory activity, piperine. Despite the role of piperine in the inhibition of the transcriptional protein...

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Detalles Bibliográficos
Autores principales: Povinelli, Ana Paula Ribeiro, Zazeri, Gabriel, Jones, Alan M., Cornélio, Marinônio Lopes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323498/
https://www.ncbi.nlm.nih.gov/pubmed/35887341
http://dx.doi.org/10.3390/ijms23147994