Synthesis of 6-Halo-Substituted Pericosine A and an Evaluation of Their Antitumor and Antiglycosidase Activities

The enantiomers of 6-fluoro-, 6-bromo-, and 6-iodopericosine A were synthesized. An efficient synthesis of both enantiomers of pericoxide via 6-bromopericosine A was also developed. These 6-halo-substituted pericosine A derivatives were evaluated in terms of their antitumor activity against three ty...

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Detalles Bibliográficos
Autores principales: Usami, Yoshihide, Mizobuchi, Yoshino, Ijuin, Mai, Yamada, Takeshi, Morita, Mizuki, Mizuki, Koji, Yoneyama, Hiroki, Harusawa, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323573/
https://www.ncbi.nlm.nih.gov/pubmed/35877731
http://dx.doi.org/10.3390/md20070438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323573/
https://www.ncbi.nlm.nih.gov/pubmed/35877731
http://dx.doi.org/10.3390/md20070438

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