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Synthesis of 6-Halo-Substituted Pericosine A and an Evaluation of Their Antitumor and Antiglycosidase Activities
The enantiomers of 6-fluoro-, 6-bromo-, and 6-iodopericosine A were synthesized. An efficient synthesis of both enantiomers of pericoxide via 6-bromopericosine A was also developed. These 6-halo-substituted pericosine A derivatives were evaluated in terms of their antitumor activity against three ty...
Autores principales: | Usami, Yoshihide, Mizobuchi, Yoshino, Ijuin, Mai, Yamada, Takeshi, Morita, Mizuki, Mizuki, Koji, Yoneyama, Hiroki, Harusawa, Shinya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323573/ https://www.ncbi.nlm.nih.gov/pubmed/35877731 http://dx.doi.org/10.3390/md20070438 |
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