Using AI-Based Evolutionary Algorithms to Elucidate Adult Brain Tumor (Glioma) Etiology Associated with IDH1 for Therapeutic Target Identification

Adult brain tumors (glioma) represent a cancer of unmet need where standard-of-care is non-curative; thus, new therapies are urgently needed. It is unclear whether isocitrate dehydrogenases (IDH1/2) when not mutated have any role in gliomagenesis or tumor growth. Nevertheless, IDH1 is overexpressed...

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Detalles Bibliográficos
Autores principales: McInerney, Caitríona E., Lynn, Joanna A., Gilmore, Alan R., Flannery, Tom, Prise, Kevin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323620/
https://www.ncbi.nlm.nih.gov/pubmed/35877430
http://dx.doi.org/10.3390/cimb44070206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323620/
https://www.ncbi.nlm.nih.gov/pubmed/35877430
http://dx.doi.org/10.3390/cimb44070206

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