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Activation of the α7 Nicotinic Acetylcholine Receptor Prevents against Microglial-Induced Inflammation and Insulin Resistance in Hypothalamic Neuronal Cells

Neuronal hypothalamic insulin resistance is implicated in energy balance dysregulation and contributes to the pathogenesis of several neurodegenerative diseases. Its development has been intimately associated with a neuroinflammatory process mainly orchestrated by activated microglial cells. In this...

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Detalles Bibliográficos
Autores principales: do Amaral, Camila Libardi, Martins, Ísis de Cássia Alves, Veras, Alana Carolina Costa, Simabuco, Fernando Moreira, Ross, Michael Glenn, Desai, Mina, Ignácio-Souza, Leticia Martins, Milanski, Marciane, Torsoni, Adriana Souza, Torsoni, Marcio Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323651/
https://www.ncbi.nlm.nih.gov/pubmed/35883638
http://dx.doi.org/10.3390/cells11142195