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Post-Transcriptional Effects of miRNAs on PCSK7 Expression and Function: miR-125a-5p, miR-143-3p, and miR-409-3p as Negative Regulators

The regulatory mechanism of PCSK7 gene is still unknown, although its encoded protein PC7 is the most ancient and highly conserved of all proprotein convertases and exhibits enzymatic and non-enzymatic functions in liver triglyceride regulation. Bioinformatics algorithms were used to predict regulat...

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Detalles Bibliográficos
Autores principales: Malakootian, Mahshid, Naeli, Parisa, Mowla, Seyed Javad, Seidah, Nabil G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323720/
https://www.ncbi.nlm.nih.gov/pubmed/35888711
http://dx.doi.org/10.3390/metabo12070588