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Unravelling the Distinct Effects of Systolic and Diastolic Blood Pressure Using Mendelian Randomisation

A true discrepancy between the effect of systolic blood pressure (SBP) and diastolic blood pressure (DBP) on cardiovascular (CV) outcomes remains unclear. This study performed two-sample Mendelian randomization (MR) using genetic instruments that exclusively predict SBP, DBP or both to dissect the i...

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Detalles Bibliográficos
Autores principales: Le, Nhu Ngoc, Tran, Tran Q. B., Lip, Stefanie, McCallum, Linsay, McClure, John, Dominiczak, Anna F., Gill, Dipender, Padmanabhan, Sandosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323763/
https://www.ncbi.nlm.nih.gov/pubmed/35886009
http://dx.doi.org/10.3390/genes13071226