Cargando…

Unravelling the Distinct Effects of Systolic and Diastolic Blood Pressure Using Mendelian Randomisation

A true discrepancy between the effect of systolic blood pressure (SBP) and diastolic blood pressure (DBP) on cardiovascular (CV) outcomes remains unclear. This study performed two-sample Mendelian randomization (MR) using genetic instruments that exclusively predict SBP, DBP or both to dissect the i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Le, Nhu Ngoc, Tran, Tran Q. B., Lip, Stefanie, McCallum, Linsay, McClure, John, Dominiczak, Anna F., Gill, Dipender, Padmanabhan, Sandosh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323763/ https://www.ncbi.nlm.nih.gov/pubmed/35886009 http://dx.doi.org/10.3390/genes13071226

Ejemplares similares

Diastolic Blood Pressure J-Curve Phenomenon in a Tertiary-Care Hypertension Clinic
por: Lip, Stefanie, et al.
Publicado: (2019)

The hidden hand of chloride in hypertension
por: McCallum, Linsay, et al.
Publicado: (2015)

Establishing plausibility of cardiovascular adverse effects of immunotherapies using Mendelian randomisation
por: Le, Nhu Ngoc, et al.
Publicado: (2023)

Rationale and Design for the LOnger-term effects of SARS-CoV-2 INfection on blood Vessels And blood pRessure (LOCHINVAR): an observational phenotyping study
por: Lip, Stefanie, et al.
Publicado: (2022)

Underrepresentation of ethnic minorities in hypertension research—a survey of enablers and barriers among South Asian and African communities in Glasgow
por: Lip, Stefanie, et al.
Publicado: (2022)

Monotherapy With Major Antihypertensive Drug Classes and Risk of Hospital Admissions for Mood Disorders
por: Boal, Angela H., et al.
Publicado: (2016)

Dietary Influence on Systolic and Diastolic Blood Pressure in the TwinsUK Cohort
por: Louca, Panayiotis, et al.
Publicado: (2020)

Longitudinal Blood Pressure Control, Long-Term Mortality, and Predictive Utility of Serum Liver Enzymes and Bilirubin in Hypertensive Patients
por: McCallum, Linsay, et al.
Publicado: (2015)

Rationale and Design of the Genotype-Blinded Trial of Torasemide for the Treatment of Hypertension (BHF UMOD)
por: McCallum, Linsay, et al.
Publicado: (2020)

OR17-05 Hypospadias Is a Predictor of Adverse Cardiometabolic Risk in Adulthood - a Case-Control Study
por: Lucas-Herald, Angela K, et al.
Publicado: (2020)

Genomics of Blood Pressure and Hypertension: Extending the Mosaic Theory Toward Stratification
por: Lip, Stefanie, et al.
Publicado: (2020)

Comparison of cardiac DTI parameters between systole and diastole
por: McGill, Laura-Ann, et al.
Publicado: (2014)

Survey and Evaluation of Hypertension Machine Learning Research
por: du Toit, Clea, et al.
Publicado: (2023)

Metabolomic profiling identifies novel associations with Electrolyte and Acid-Base Homeostatic patterns
por: Menni, Cristina, et al.
Publicado: (2019)

The total and direct effects of systolic and diastolic blood pressure on cardiovascular disease and longevity using Mendelian randomisation
por: Chan, Io Ieong, et al.
Publicado: (2021)

Recent Findings in the Genetics of Blood Pressure: How to Apply in Practice or Is a Moonshot Required?
por: Padmanabhan, Sandosh, et al.
Publicado: (2018)

Genome-Wide Association Studies of Hypertension: Light at the End of the Tunnel
por: Hastie, Claire E., et al.
Publicado: (2010)

The evolution of mendelian randomization for investigating drug effects
por: Gill, Dipender, et al.
Publicado: (2022)

Layer-specific systolic and diastolic strain in hypertensive patients with and without mild diastolic dysfunction
por: Sharif, Hisham, et al.
Publicado: (2018)

Standardizing the reporting of Mendelian randomization studies
por: Au Yeung, Shiu Lun, et al.
Publicado: (2023)

Unravelling the role of host plant expansion in the diversification of a Neotropical butterfly genus
por: McClure, Melanie, et al.
Publicado: (2016)

Genetics of hypertension: From experimental animals to humans
por: Delles, Christian, et al.
Publicado: (2010)

Modeling Pathologies of Diastolic and Systolic Heart Failure
por: Genet, M., et al.
Publicado: (2015)

Cardiovascular and Renal Risk Factors and Complications Associated With COVID-19
por: Touyz, Rhian M., et al.
Publicado: (2021)

The importance of clinical pharmacokinetic–pharmacodynamic studies in unraveling the determinants of early and late tuberculosis outcomes
por: McCallum, Andrew D, et al.
Publicado: (2017)

Systolic, diastolic blood pressure and pulse pressure and risk of stroke in young aged patients with atrial fibrillation
por: Lee, S R, et al.
Publicado: (2023)

Novel Strategies for the Detection of Systolic and Diastolic Heart Failure
por: Bolt, Cara Lodewijks-vd, et al.
Publicado: (2009)

Natriuretic peptides in the detection of preclinical diastolic or systolic dysfunction
por: Luers, Claus, et al.
Publicado: (2010)

Note on the Utility of the Systole and Diastole of the Uterus during Uterogestation
por: Oliver, James
Publicado: (1909)

Systolic and diastolic function in chronic spinal cord injury
por: Ditterline, Bonnie Legg, et al.
Publicado: (2020)

Left Ventricular Diastolic and Systolic Functions in Patients with Hypothyroidism †
por: Tafarshiku, Rina, et al.
Publicado: (2020)

Association of Serum Magnesium Levels With Risk of Intracranial Aneurysm: A Mendelian Randomization Study
por: Larsson, Susanna C., et al.
Publicado: (2021)

Systemic iron status and maternal pregnancy complications: A Mendelian randomization study
por: Rogne, Tormod, et al.
Publicado: (2022)

Genetically proxied lean mass and risk of Alzheimer’s disease: mendelian randomisation study
por: Daghlas, Iyas, et al.
Publicado: (2023)

Iron Status and Risk of Stroke: A Mendelian Randomization Study
por: Gill, Dipender, et al.
Publicado: (2018)

Sparse dimensionality reduction approaches in Mendelian randomisation with highly correlated exposures
por: Karageorgiou, Vasileios, et al.
Publicado: (2023)

An empirical investigation into the impact of winner’s curse on estimates from Mendelian randomization
por: Jiang, Tao, et al.
Publicado: (2022)

Quantitative assessment of systolic and diastolic function in patients with systemic amyloidosis
por: Kuetting, Daniel, et al.
Publicado: (2016)

Systolic and diastolic dysfunction affects kidney outcomes in hospitalized patients
por: Choi, Jae Shin, et al.
Publicado: (2018)

Depletion of cardiac cardiolipin synthase alters systolic and diastolic function
por: Smeir, Elia, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_e3pmq5dh39moqio9gbpbe6ok5j