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4-Substituted Thieno[3,2-d]pyrimidines as Dual-Stage Antiplasmodial Derivatives

Malaria remains one of the major health problems worldwide. The increasing resistance of Plasmodium to approved antimalarial drugs requires the development of novel antiplasmodial agents that can effectively prevent and/or treat this disease. Based on the structure of Gamhepathiopine, a 2-tert-butyl...

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Detalles Bibliográficos
Autores principales: Lagardère, Prisca, Mustière, Romain, Amanzougaghene, Nadia, Hutter, Sébastien, Franetich, Jean-François, Azas, Nadine, Vanelle, Patrice, Verhaeghe, Pierre, Primas, Nicolas, Mazier, Dominique, Masurier, Nicolas, Lisowski, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323797/
https://www.ncbi.nlm.nih.gov/pubmed/35890119
http://dx.doi.org/10.3390/ph15070820