Novel Esomeprazole Magnesium-Loaded Dual-Release Mini-Tablet Polycap: Formulation, Optimization, Characterization, and In Vivo Evaluation in Beagle Dogs

Esomeprazole magnesium (EMP) is a proton pump inhibitor (PPI) that reduces acid secretion. EMP has a short plasma half-life (approximately 1.3 h); hence, nocturnal acid breakthrough (NAB) frequently occurs, disturbing the patient’s nighttime comfort and sleep. We aimed to develop a novel esomeprazol...

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Detalles Bibliográficos
Autores principales: Kwon, Taek Kwan, Kang, Ji-Hyun, Na, Sang-Beom, Kim, Jae Ho, Kim, Yong-Il, Kim, Dong-Wook, Park, Chun-Woong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323828/
https://www.ncbi.nlm.nih.gov/pubmed/35890307
http://dx.doi.org/10.3390/pharmaceutics14071411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323828/
https://www.ncbi.nlm.nih.gov/pubmed/35890307
http://dx.doi.org/10.3390/pharmaceutics14071411

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