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The Combination of Molnupiravir with Nirmatrelvir or GC376 Has a Synergic Role in the Inhibition of SARS-CoV-2 Replication In Vitro

Introduction: The development of effective vaccines has partially mitigated the trend of the SARS-CoV-2 pandemic; however, the need for orally administered antiviral drugs persists. This study aims to investigate the activity of molnupiravir in combination with nirmatrelvir or GC376 on SARS-CoV-2 to...

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Detalles Bibliográficos
Autores principales: Gidari, Anna, Sabbatini, Samuele, Schiaroli, Elisabetta, Bastianelli, Sabrina, Pierucci, Sara, Busti, Chiara, Comez, Lucia, Libera, Valeria, Macchiarulo, Antonio, Paciaroni, Alessandro, Vicenti, Ilaria, Zazzi, Maurizio, Francisci, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323947/
https://www.ncbi.nlm.nih.gov/pubmed/35889194
http://dx.doi.org/10.3390/microorganisms10071475