High PANX1 Expression Leads to Neutrophil Recruitment and the Formation of a High Adenosine Immunosuppressive Tumor Microenvironment in Basal-like Breast Cancer

SIMPLE SUMMARY: A high adenosine level is an important characteristic of the tumor microenvironment (TME) in breast cancer. Pannexin 1 (PANX1) can release intracellular ATP to the extracellular space and elevate extracellular ATP (exATP) levels under physiological conditions. PANX1 has been found to...

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Detalles Bibliográficos
Autores principales: Chen, Wuzhen, Li, Baizhou, Jia, Fang, Li, Jiaxin, Huang, Huanhuan, Ni, Chao, Xia, Wenjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323990/
https://www.ncbi.nlm.nih.gov/pubmed/35884429
http://dx.doi.org/10.3390/cancers14143369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323990/
https://www.ncbi.nlm.nih.gov/pubmed/35884429
http://dx.doi.org/10.3390/cancers14143369

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