Regulated Expression of lpxC Allows for Reduction of Endotoxicity in Bordetella pertussis

The Gram-negative bacterium Bordetella pertussis is the causative agent of a respiratory infection known as whooping cough. Previously developed whole-cell pertussis vaccines were effective, but appeared to be too reactogenic mainly due to the presence of lipopolysaccharide (LPS, also known as endot...

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Detalles Bibliográficos
Autores principales: Pérez-Ortega, Jesús, van Boxtel, Ria, de Jonge, Eline F., Tommassen, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324023/
https://www.ncbi.nlm.nih.gov/pubmed/35887374
http://dx.doi.org/10.3390/ijms23148027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324023/
https://www.ncbi.nlm.nih.gov/pubmed/35887374
http://dx.doi.org/10.3390/ijms23148027

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