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Regulated Expression of lpxC Allows for Reduction of Endotoxicity in Bordetella pertussis
The Gram-negative bacterium Bordetella pertussis is the causative agent of a respiratory infection known as whooping cough. Previously developed whole-cell pertussis vaccines were effective, but appeared to be too reactogenic mainly due to the presence of lipopolysaccharide (LPS, also known as endot...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324023/ https://www.ncbi.nlm.nih.gov/pubmed/35887374 http://dx.doi.org/10.3390/ijms23148027 |