A Novel Late-Stage Autophagy Inhibitor That Efficiently Targets Lysosomes Inducing Potent Cytotoxic and Sensitizing Effects in Lung Cancer

SIMPLE SUMMARY: Lung cancer is the main cause of cancer-related deaths worldwide, mainly due to treatment resistance. For that reason, it is necessary to develop novel therapeutic strategies to overcome this phenomenon. The aim of our study was to design and characterize a synthetic anionophore, LAI...

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Detalles Bibliográficos
Autores principales: Molero-Valenzuela, Adrià, Fontova, Pere, Alonso-Carrillo, Daniel, Carreira-Barral, Israel, Torres, Ana Aurora, García-Valverde, María, Benítez-García, Cristina, Pérez-Tomás, Ricardo, Quesada, Roberto, Soto-Cerrato, Vanessa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324127/
https://www.ncbi.nlm.nih.gov/pubmed/35884450
http://dx.doi.org/10.3390/cancers14143387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324127/
https://www.ncbi.nlm.nih.gov/pubmed/35884450
http://dx.doi.org/10.3390/cancers14143387

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