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Enlightening the “Spirit Molecule”: Photomodulation of the 5‐HT(2A) Receptor by a Light‐Controllable N,N‐Dimethyltryptamine Derivative

Classical psychedelics are a group of hallucinogens which trigger non‐ordinary states of consciousness through activation of the 5‐HT(2A) receptor (5‐HT(2A)R) in the brain. However, the exact mechanism of how 5‐HT(2A)R agonism alters perception remains elusive. When studying receptor signaling, tool...

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Detalles Bibliográficos
Autores principales: Gerwe, Hubert, He, Feng, Pottie, Eline, Stove, Christophe, Decker, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324199/
https://www.ncbi.nlm.nih.gov/pubmed/35349196
http://dx.doi.org/10.1002/anie.202203034