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Mutagenic Analysis of the HIV Restriction Factor Shiftless

The interferon-induced host cell protein shiftless (SFL) was reported to inhibit human immunodeficiency virus (HIV) infection by blocking the –1 programmed ribosomal frameshifting (–1PRF) required for expression of the Gag-Pol polyprotein. However, it is not clear how SFL inhibits –1PRF. To address...

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Detalles Bibliográficos
Autores principales: Jäger, Niklas, Ayyub, Shreya Ahana, Korniy, Natalia, Peske, Frank, Hoffmann, Markus, Rodnina, Marina V., Pöhlmann, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324250/
https://www.ncbi.nlm.nih.gov/pubmed/35891432
http://dx.doi.org/10.3390/v14071454