Yohimbine, an α2-Adrenoceptor Antagonist, Suppresses PDGF-BB-Stimulated Vascular Smooth Muscle Cell Proliferation by Downregulating the PLCγ1 Signaling Pathway

Yohimbine (YOH) has antiproliferative effects against breast cancer and pancreatic cancer; however, its effects on vascular proliferative diseases such as atherosclerosis remain unknown. Accordingly, we investigated the inhibitory mechanisms of YOH in vascular smooth muscle cells (VSMCs) stimulated...

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Detalles Bibliográficos
Autores principales: Chiu, Chih-Wei, Hsieh, Cheng-Ying, Yang, Chih-Hao, Tsai, Jie-Heng, Huang, Shih-Yi, Sheu, Joen-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324260/
https://www.ncbi.nlm.nih.gov/pubmed/35887391
http://dx.doi.org/10.3390/ijms23148049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324260/
https://www.ncbi.nlm.nih.gov/pubmed/35887391
http://dx.doi.org/10.3390/ijms23148049

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