The Patterning and Proportion of Charged Residues in the Arginine-Rich Mixed-Charge Domain Determine the Membrane-Less Organelle Targeted by the Protein

Membrane-less organelles (MLOs) are formed by biomolecular liquid–liquid phase separation (LLPS). Proteins with charged low-complexity domains (LCDs) are prone to phase separation and localize to MLOs, but the mechanism underlying the distributions of such proteins to specific MLOs remains poorly un...

Descripción completa

Detalles Bibliográficos
Autores principales: Miyagi, Tamami, Yamazaki, Rio, Ueda, Koji, Narumi, Satoshi, Hayamizu, Yuhei, Uji-i, Hiroshi, Kuroda, Masahiko, Kanekura, Kohsuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324279/
https://www.ncbi.nlm.nih.gov/pubmed/35887012
http://dx.doi.org/10.3390/ijms23147658

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324279/
https://www.ncbi.nlm.nih.gov/pubmed/35887012
http://dx.doi.org/10.3390/ijms23147658

Ejemplares similares