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The Patterning and Proportion of Charged Residues in the Arginine-Rich Mixed-Charge Domain Determine the Membrane-Less Organelle Targeted by the Protein

Membrane-less organelles (MLOs) are formed by biomolecular liquid–liquid phase separation (LLPS). Proteins with charged low-complexity domains (LCDs) are prone to phase separation and localize to MLOs, but the mechanism underlying the distributions of such proteins to specific MLOs remains poorly un...

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Detalles Bibliográficos
Autores principales:	Miyagi, Tamami, Yamazaki, Rio, Ueda, Koji, Narumi, Satoshi, Hayamizu, Yuhei, Uji-i, Hiroshi, Kuroda, Masahiko, Kanekura, Kohsuke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324279/ https://www.ncbi.nlm.nih.gov/pubmed/35887012 http://dx.doi.org/10.3390/ijms23147658

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