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Inflammatory Response, Immunosuppression and Arginase Activity after Cardiac Surgery Using Cardiopulmonary Bypass

Background: Major surgeries suppress patients’ cellular immunity for several days, but the mechanisms underlying this T-cell dysfunction are not well understood. A decreased L-Arginine (L-Arg) level may inhibit T-cell function. Arginase 1 (Arg 1) is induced after traumatic injury, leading to molecul...

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Detalles Bibliográficos
Autores principales: Rodríguez-López, José María, Iglesias-González, José Luis, Lozano-Sánchez, Francisco Santiago, Palomero-Rodríguez, Miguel Ángel, Sánchez-Conde, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324329/
https://www.ncbi.nlm.nih.gov/pubmed/35887950
http://dx.doi.org/10.3390/jcm11144187