Linearolactone Induces Necrotic-like Death in Giardia intestinalis Trophozoites: Prediction of a Likely Target

Linearolactone (LL) is a neo-clerodane type diterpene that has been shown to exert giardicidal effects; however, its mechanism of action is unknown. This work analyzes the cytotoxic effect of LL on Giardia intestinalis trophozoites and identifies proteins that could be targeted by this active natura...

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Detalles Bibliográficos
Autores principales: Argüello-García, Raúl, Calzada, Fernando, Chávez-Munguía, Bibiana, Matus-Meza, Audifás-Salvador, Bautista, Elihú, Barbosa, Elizabeth, Velazquez, Claudia, Hernández-Caballero, Marta Elena, Ordoñez-Razo, Rosa Maria, Velázquez-Domínguez, José Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324340/
https://www.ncbi.nlm.nih.gov/pubmed/35890108
http://dx.doi.org/10.3390/ph15070809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324340/
https://www.ncbi.nlm.nih.gov/pubmed/35890108
http://dx.doi.org/10.3390/ph15070809

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