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Molecular Characterization of a DNA Polymerase from Thermus thermophilus MAT72 Phage vB_Tt72: A Novel Type-A Family Enzyme with Strong Proofreading Activity

We present a structural and functional analysis of the DNA polymerase of thermophilic Thermus thermophilus MAT72 phage vB_Tt72. The enzyme shows low sequence identity (<30%) to the members of the type-A family of DNA polymerases, except for two yet uncharacterized DNA polymerases of T. thermophil...

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Detalles Bibliográficos
Autores principales: Dorawa, Sebastian, Werbowy, Olesia, Plotka, Magdalena, Kaczorowska, Anna-Karina, Makowska, Joanna, Kozlowski, Lukasz P., Fridjonsson, Olafur H., Hreggvidsson, Gudmundur O., Aevarsson, Arnthór, Kaczorowski, Tadeusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324360/
https://www.ncbi.nlm.nih.gov/pubmed/35887293
http://dx.doi.org/10.3390/ijms23147945