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Upregulation of Mineralocorticoid Receptor Contributes to Development of Salt-Sensitive Hypertension after Ischemia–Reperfusion Injury in Rats

The ischemia–reperfusion injury (IRI) of rat kidneys is used as a model of acute kidney injury. Salt-sensitive hypertension occurs in rats after IRI, and the distal nephrons play important roles in the development of this condition. We investigated the role of the mineralocorticoid receptor (MR) in...

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Detalles Bibliográficos
Autores principales: Matsumoto, Takumi, Doi, Shigehiro, Nakashima, Ayumu, Ike, Takeshi, Sasaki, Kensuke, Masaki, Takao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324399/
https://www.ncbi.nlm.nih.gov/pubmed/35887178
http://dx.doi.org/10.3390/ijms23147831