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Neonatal Deletion of Hand1 and Hand2 within Murine Cardiac Conduction System Reveals a Novel Role for HAND2 in Rhythm Homeostasis

The cardiac conduction system, a network of specialized cells, is required for the functioning of the heart. The basic helix loop helix factors Hand1 and Hand2 are required for cardiac morphogenesis and have been implicated in cardiac conduction system development and maintenance. Here we use embryo...

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Detalles Bibliográficos
Autores principales: George, Rajani M., Guo, Shuai, Firulli, Beth A., Rubart, Michael, Firulli, Anthony B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324487/
https://www.ncbi.nlm.nih.gov/pubmed/35877576
http://dx.doi.org/10.3390/jcdd9070214