Cargando…
Neonatal Deletion of Hand1 and Hand2 within Murine Cardiac Conduction System Reveals a Novel Role for HAND2 in Rhythm Homeostasis
The cardiac conduction system, a network of specialized cells, is required for the functioning of the heart. The basic helix loop helix factors Hand1 and Hand2 are required for cardiac morphogenesis and have been implicated in cardiac conduction system development and maintenance. Here we use embryo...
Autores principales: | George, Rajani M., Guo, Shuai, Firulli, Beth A., Rubart, Michael, Firulli, Anthony B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324487/ https://www.ncbi.nlm.nih.gov/pubmed/35877576 http://dx.doi.org/10.3390/jcdd9070214 |
Ejemplares similares
-
Deletion of a Hand1 lncRNA-Containing Septum Transversum Enhancer Alters lncRNA Expression but Is Not Required for Hand1 Expression
por: George, Rajani M., et al.
Publicado: (2021) -
Defective Hand1 phosphoregulation uncovers essential roles for Hand1 in limb morphogenesis
por: Firulli, Beth A., et al.
Publicado: (2017) -
Hand factor ablation causes defective left ventricular chamber development and compromised adult cardiac function
por: Vincentz, Joshua W., et al.
Publicado: (2017) -
Mis-Expression of a Cranial Neural Crest Cell-Specific Gene Program in Cardiac Neural Crest Cells Modulates HAND Factor Expression, Causing Cardiac Outflow Tract Phenotypes
por: Vincentz, Joshua W., et al.
Publicado: (2020) -
Hands of rhythm
por: Hidalgo, Giovanni
Publicado: (1997)