Subtype of Neuroblastoma Cells with High KIT Expression Are Dependent on KIT and Its Knockdown Induces Compensatory Activation of Pro-Survival Signaling

Neuroblastoma (NB) is a pediatric cancer with high clinical and molecular heterogeneity, and patients with high-risk tumors have limited treatment options. Receptor tyrosine kinase KIT has been identified as a potential marker of high-risk NB and a promising target for NB treatment. We investigated...

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Detalles Bibliográficos
Autores principales: Lebedev, Timofey, Buzdin, Anton, Khabusheva, Elmira, Spirin, Pavel, Suntsova, Maria, Sorokin, Maxim, Popenko, Vladimir, Rubtsov, Petr, Prassolov, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324519/
https://www.ncbi.nlm.nih.gov/pubmed/35887076
http://dx.doi.org/10.3390/ijms23147724

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324519/
https://www.ncbi.nlm.nih.gov/pubmed/35887076
http://dx.doi.org/10.3390/ijms23147724

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