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A Novel Cre/lox71-Based System for Inducible Expression of Recombinant Proteins and Genome Editing

In this study, we developed a novel Cre/lox71-based system for the controlled transient expression of target genes. We used the bacteriophage P1 Cre recombinase, which harbors a short, highly specific DNA-binding site and does not have endogenous binding sites within mouse or human genomes. Fusing t...

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Detalles Bibliográficos
Autores principales: Karagyaur, Maxim, Dyikanov, Daniyar, Tyurin-Kuzmin, Pyotr, Dzhauari, Stalik, Skryabina, Mariya, Vigovskiy, Maksim, Primak, Alexandra, Kalinina, Natalia, Tkachuk, Vsevolod
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324666/
https://www.ncbi.nlm.nih.gov/pubmed/35883584
http://dx.doi.org/10.3390/cells11142141