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Galactomannan-Decorated Lipidic Nanocarrier for Gene Supplementation Therapy in Fabry Disease

Gene supplementation therapy with plasmid DNA (pDNA) represents one of the most promising strategies for the treatment of monogenic diseases such as Fabry disease (FD). In the present work, we developed a solid lipid nanoparticles (SLN)-based non-viral vector with a size below 100 nm, and decorated...

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Detalles Bibliográficos
Autores principales: Rodríguez-Castejón, Julen, Gómez-Aguado, Itziar, Beraza-Millor, Marina, Solinís, María Ángeles, del Pozo-Rodríguez, Ana, Rodríguez-Gascón, Alicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324688/
https://www.ncbi.nlm.nih.gov/pubmed/35889565
http://dx.doi.org/10.3390/nano12142339