Molecular Modelling of NONO and SFPQ Dimerization Process and RNA Recognition Mechanism

NONO and SFPQ are involved in multiple nuclear processes (e.g., pre-mRNA splicing, DNA repair, and transcriptional regulation). These proteins, along with NEAT1, enable paraspeckle formation, thus promoting multiple myeloma cell survival. In this paper, we investigate NONO and SFPQ dimer stability,...

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Detalles Bibliográficos
Autores principales: Laurenzi, Tommaso, Palazzolo, Luca, Taiana, Elisa, Saporiti, Simona, Ben Mariem, Omar, Guerrini, Uliano, Neri, Antonino, Eberini, Ivano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324803/
https://www.ncbi.nlm.nih.gov/pubmed/35886974
http://dx.doi.org/10.3390/ijms23147626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324803/
https://www.ncbi.nlm.nih.gov/pubmed/35886974
http://dx.doi.org/10.3390/ijms23147626

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