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Molecular Modelling of NONO and SFPQ Dimerization Process and RNA Recognition Mechanism
NONO and SFPQ are involved in multiple nuclear processes (e.g., pre-mRNA splicing, DNA repair, and transcriptional regulation). These proteins, along with NEAT1, enable paraspeckle formation, thus promoting multiple myeloma cell survival. In this paper, we investigate NONO and SFPQ dimer stability,...
Autores principales: | Laurenzi, Tommaso, Palazzolo, Luca, Taiana, Elisa, Saporiti, Simona, Ben Mariem, Omar, Guerrini, Uliano, Neri, Antonino, Eberini, Ivano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324803/ https://www.ncbi.nlm.nih.gov/pubmed/35886974 http://dx.doi.org/10.3390/ijms23147626 |
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