Cargando…

Stereoinvertive Nucleophilic Substitution at Quaternary Carbon Stereocenters of Cyclopropyl Ketones and Ethers

A highly regio‐ and diastereoselective nucleophilic substitution at the quaternary carbon stereocenter of cyclopropyl ketones and cyclopropyl carbinol derivatives using TMSBr, DMPSCl and TMSN(3) as nucleophiles has been developed. A variety of acyclic tertiary alkyl bromides, chlorides and azides we...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Xu, Marek, Ilan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324837/ https://www.ncbi.nlm.nih.gov/pubmed/35471589 http://dx.doi.org/10.1002/anie.202203673

Ejemplares similares

Stereoselective Construction of Tertiary Homoallyl Alcohols and Ethers by Nucleophilic Substitution at Quaternary Carbon Stereocenters
por: Chen, Xu, et al.
Publicado: (2022)

Highly Diastereoselective Preparation of Tertiary Alkyl Isonitriles by Stereoinvertive Nucleophilic Substitution at a Nonclassical Carbocation
por: Chen, Xu, et al.
Publicado: (2023)

Stereospecific Construction of Quaternary Carbon Stereocenters from Quaternary Carbon Stereocenters
por: Patel, Kaushalendra, et al.
Publicado: (2022)

Stereospecific nucleophilic substitution at tertiary and quaternary stereocentres
por: Lanke, Veeranjaneyulu, et al.
Publicado: (2020)

Preparation of Distant Quaternary Carbon Stereocenters by Double Selective Ring‐Opening of 1,1‐Biscyclopropyl Methanol Derivatives
por: Siddaraju, Yogesh, et al.
Publicado: (2022)

Organocatalytic enantioselective S(N)1-type dehydrative nucleophilic substitution: access to bis(indolyl)methanes bearing quaternary carbon stereocenters
por: Zhu, Wen-Run, et al.
Publicado: (2021)

Biocatalytic Conversion of Cyclic Ketones Bearing α‐Quaternary Stereocenters into Lactones in an Enantioselective Radical Approach to Medium‐Sized Carbocycles
por: Morrill, Charlotte, et al.
Publicado: (2018)

Synthesis of (Het)aryl 2-(2-hydroxyaryl)cyclopropyl Ketones
por: Fadeev, Alexander A., et al.
Publicado: (2020)

Borylated Cyclopropanes as Spring-Loaded Entities: Access to Vicinal Tertiary and Quaternary Carbon Stereocenters in Acyclic Systems
por: Augustin, André U., et al.
Publicado: (2022)

Catalytic enantioselective construction of vicinal quaternary carbon stereocenters
por: Zhou, Feng, et al.
Publicado: (2020)

Enantioselective construction of triaryl-substituted all-carbon quaternary stereocenters via organocatalytic arylation of oxindoles with azonaphthalenes
por: Chen, Pengquan, et al.
Publicado: (2023)

Stereodivergent synthesis of vicinal quaternary-quaternary stereocenters and bioactive hyperolactones
por: Zheng, Haifeng, et al.
Publicado: (2018)

Nickel-catalyzed enantioselective α-heteroarylation of ketones via C–F bond activation to construct all-carbon quaternary stereocenters
por: Gu, Xiaodong, et al.
Publicado: (2022)

Cross-dehydrogenative coupling enables enantioselective access to CF(3)-substituted all-carbon quaternary stereocenters
por: Pan, Xiaoguang, et al.
Publicado: (2020)

Enantioselective Construction of Remote Quaternary Stereocenters
por: Mei, Tian-Sheng, et al.
Publicado: (2014)

Asymmetric construction of acyclic quaternary stereocenters via direct enantioselective additions of α-alkynyl ketones to allenamides
por: Wang, Jiawen, et al.
Publicado: (2021)

Doubly stereoconvergent construction of vicinal all-carbon quaternary and tertiary stereocenters by Cu/Mg-catalyzed propargylic substitution
por: Pu, Xiang, et al.
Publicado: (2022)

Diastereodivergent combined carbometalation/zinc homologation/C–C fragmentation reaction as an efficient tool to prepare acyclic allylic quaternary carbon stereocenters
por: Roy, Sudipta Raha, et al.
Publicado: (2016)

Forging Fluorine‐Containing Quaternary Stereocenters by a Light‐Driven Organocatalytic Aldol Desymmetrization Process
por: Cuadros, Sara, et al.
Publicado: (2017)

Stereospecific Cross Couplings To Set Benzylic, All-Carbon Quaternary Stereocenters in High Enantiopurity
por: Zhou, Qi, et al.
Publicado: (2016)

Preparation of Chiral Enantioenriched Densely Substituted Cyclopropyl Azoles, Amines, and Ethers via Formal S(N)2′ Substitution of Bromocylopropanes
por: Straub, Hillary, et al.
Publicado: (2022)

Catalytic Enantioselective Entry to Triflones Featuring a Quaternary Stereocenter
por: Franco, Francesca, et al.
Publicado: (2022)

Quaternary Stereocenters via an Enantioconvergent Catalytic S(N)1 Reaction
por: Wendlandt, Alison E., et al.
Publicado: (2018)

Diastereodivergent Synthesis of Cyclopentyl Boronic Esters Bearing Contiguous Fully Substituted Stereocenters
por: Fairchild, Molly E., et al.
Publicado: (2022)

Enantioselective Synthesis of Acyclic Orthogonally Functionalized Compounds Bearing a Quaternary Stereocenter Using Chiral Ammonium Salt Catalysis
por: Röser, Katharina, et al.
Publicado: (2021)

Direct catalytic enantioselective amination of ketones for the formation of tri- and tetrasubstituted stereocenters
por: Trost, B. M., et al.
Publicado: (2018)

Construction of polycyclic structures with vicinal all-carbon quaternary stereocenters via an enantioselective photoenolization/Diels–Alder reaction
por: Hou, Min, et al.
Publicado: (2021)

Enantioselective synthesis of cis-hydrobenzofurans bearing all-carbon quaternary stereocenters and application to total synthesis of (‒)-morphine
por: Zhang, Qing, et al.
Publicado: (2019)

Enantioselective Synthesis of Aza-Flavanones with an All-Carbon Quaternary Stereocenter via NHC-Catalyzed Intramolecular Annulation
por: Barańska, Izabela, et al.
Publicado: (2023)

Directed Diastereoselective Cyclopropanation and Epoxidation of Alkenyl Cyclopropyl Carbinol Derivatives
por: Cohen, Anthony, et al.
Publicado: (2022)

Nucleophilic Thiols Reductively Cleave Ether Linkages in Lignin Model Polymers and Lignin
por: Klinger, Grace E., et al.
Publicado: (2020)

Asymmetric Construction of All-Carbon Quaternary Stereocenters by Chiral-Auxiliary-Mediated Claisen Rearrangement and Total Synthesis of (+)-Bakuchiol
por: Takao, Ken-ichi, et al.
Publicado: (2012)

Organocatalytic asymmetric formal oxidative coupling for the construction of all-aryl quaternary stereocenters
por: Li, Zhiyang, et al.
Publicado: (2021)

SmI(2)-Catalyzed Intermolecular Coupling of Cyclopropyl Ketones and Alkynes: A Link between Ketone Conformation and Reactivity
por: Agasti, Soumitra, et al.
Publicado: (2021)

Study on the Overmolding Process of Carbon-Fiber-Reinforced Poly (Aryl Ether Ketone) (PAEK)/Poly (Ether Ether Ketone) (PEEK) Thermoplastic Composites
por: Zhao, Ziyue, et al.
Publicado: (2023)

Construction of 4-hydroxycoumarin derivatives with adjacent quaternary and tertiary stereocenters via ternary catalysis
por: Zhang, Mengchu, et al.
Publicado: (2023)

Comparison of osteogenic potential of poly-ether-ether-ketone with titanium-coated poly-ether-ether-ketone and titanium-blended poly-ether-ether-ketone: An in vitro study
por: Kumar, T. Anjan, et al.
Publicado: (2017)

Understanding the Reinforcement of Graphene in Poly(Ether Ether Ketone)/Carbon Fibre Laminates
por: Flores, Araceli, et al.
Publicado: (2021)

Organocatalytic sulfa-Michael/aldol cascade: constructing functionalized 2,5-dihydrothiophenes bearing a quaternary carbon stereocenter
por: Zhu, Xiao-Yu, et al.
Publicado: (2018)

A Free Silanide from Nucleophilic Substitution at Silicon(II)
por: Witteman, Léon, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_vh2n3ij2dp0ef0n2jlei4oqp2s