Cargando…
A microRNA or messenger RNA point of departure estimates an apical endpoint point of departure in a rat developmental toxicity model
Traditional developmental toxicity testing practice examines fetal apical endpoints to identify a point of departure (POD) for risk assessment. A potential new testing paradigm involves deriving a POD from a comprehensive analysis of molecular‐level change. Here, the rat ketoconazole endocrine‐media...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley & Sons, Inc.
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9324934/ https://www.ncbi.nlm.nih.gov/pubmed/35596682 http://dx.doi.org/10.1002/bdr2.2046 |