Formation of Breslow Intermediates from N‐Heterocyclic Carbenes and Aldehydes Involves Autocatalysis by the Breslow Intermediate, and a Hemiacetal

Under aprotic conditions, the stoichiometric reaction of N‐heterocyclic carbenes (NHCs) such as imidazolidin‐2‐ylidenes with aldehydes affords Breslow Intermediates (BIs), involving a formal 1,2‐C‐to‐O proton shift. We herein report kinetic studies (NMR), complemented by DFT calculations, on the mec...

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Detalles Bibliográficos
Autores principales: Wessels, Alina, Klussmann, Martin, Breugst, Martin, Schlörer, Nils E., Berkessel, Albrecht
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325009/
https://www.ncbi.nlm.nih.gov/pubmed/35238462
http://dx.doi.org/10.1002/anie.202117682

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325009/
https://www.ncbi.nlm.nih.gov/pubmed/35238462
http://dx.doi.org/10.1002/anie.202117682

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