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Formation of Breslow Intermediates from N‐Heterocyclic Carbenes and Aldehydes Involves Autocatalysis by the Breslow Intermediate, and a Hemiacetal

Under aprotic conditions, the stoichiometric reaction of N‐heterocyclic carbenes (NHCs) such as imidazolidin‐2‐ylidenes with aldehydes affords Breslow Intermediates (BIs), involving a formal 1,2‐C‐to‐O proton shift. We herein report kinetic studies (NMR), complemented by DFT calculations, on the mec...

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Detalles Bibliográficos
Autores principales:	Wessels, Alina, Klussmann, Martin, Breugst, Martin, Schlörer, Nils E., Berkessel, Albrecht
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325009/ https://www.ncbi.nlm.nih.gov/pubmed/35238462 http://dx.doi.org/10.1002/anie.202117682

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