The Synergistic Inhibition of Coronavirus Replication and Induced Cytokine Production by Ciclesonide and the Tylophorine-Based Compound Dbq33b

Ciclesonide is an inhaled corticosteroid used to treat asthma and has been repurposed as a treatment for mildly ill COVID-19 patients, but its precise mechanism of action is unclear. Herein, we report that ciclesonide blocks the coronavirus-induced production of the cytokines IL-6, IL-8, and MCP-1 b...

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Detalles Bibliográficos
Autores principales: Lee, Yue-Zhi, Hsu, Hsing-Yu, Yang, Cheng-Wei, Lin, Yi-Ling, Chang, Sui-Yuan, Yang, Ruey-Bing, Liang, Jian-Jong, Chao, Tai-Ling, Liao, Chun-Che, Kao, Han-Chieh, Chang, Jang-Yang, Sytwu, Huey-Kang, Chen, Chiung-Tong, Lee, Shiow-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325102/
https://www.ncbi.nlm.nih.gov/pubmed/35890406
http://dx.doi.org/10.3390/pharmaceutics14071511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325102/
https://www.ncbi.nlm.nih.gov/pubmed/35890406
http://dx.doi.org/10.3390/pharmaceutics14071511

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