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Targeted Genotyping of MIS-C Patients Reveals a Potential Alternative Pathway Mediated Complement Dysregulation during COVID-19 Infection

Complement dysregulation has been documented in adults with COVID-19 and implicated in relevant pediatric inflammatory responses against SARS-CoV-2. We propose that signatures of complement missense coding SNPs associated with dysregulation could also be identified in children with multisystem infla...

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Detalles Bibliográficos
Autores principales: Gavriilaki, Eleni, Tsiftsoglou, Stefanos A., Touloumenidou, Tasoula, Farmaki, Evangelia, Panagopoulou, Paraskevi, Michailidou, Elissavet, Koravou, Evaggelia-Evdoxia, Mavrikou, Ioulia, Iosifidis, Elias, Tsiatsiou, Olga, Papadimitriou, Eleni, Papadopoulou-Alataki, Efimia, Papayanni, Penelope Georgia, Varelas, Christos, Kokkoris, Styliani, Papalexandri, Apostolia, Fotoulaki, Maria, Galli-Tsinopoulou, Assimina, Zafeiriou, Dimitrios, Roilides, Emmanuel, Sakellari, Ioanna, Anagnostopoulos, Achilles, Tragiannidis, Athanasios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325260/
https://www.ncbi.nlm.nih.gov/pubmed/35877417
http://dx.doi.org/10.3390/cimb44070193