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Cold Denaturation of Proteins in the Absence of Solvent: Implications for Protein Storage

The effect of temperature on the stability of proteins is well explored above 298 K, but harder to track experimentally below 273 K. Variable‐temperature ion mobility mass spectrometry (VT IM‐MS) allows us to measure the structure of molecules at sub‐ambient temperatures. Here we monitor conformatio...

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Detalles Bibliográficos
Autores principales: Norgate, Emma L., Upton, Rosie, Hansen, Kjetil, Bellina, Bruno, Brookes, C., Politis, Argyris, Barran, Perdita E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325448/
https://www.ncbi.nlm.nih.gov/pubmed/35313047
http://dx.doi.org/10.1002/anie.202115047