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Cold Denaturation of Proteins in the Absence of Solvent: Implications for Protein Storage
The effect of temperature on the stability of proteins is well explored above 298 K, but harder to track experimentally below 273 K. Variable‐temperature ion mobility mass spectrometry (VT IM‐MS) allows us to measure the structure of molecules at sub‐ambient temperatures. Here we monitor conformatio...
Autores principales: | Norgate, Emma L., Upton, Rosie, Hansen, Kjetil, Bellina, Bruno, Brookes, C., Politis, Argyris, Barran, Perdita E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325448/ https://www.ncbi.nlm.nih.gov/pubmed/35313047 http://dx.doi.org/10.1002/anie.202115047 |
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