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A pilot study of ADRA2A genotype association with doses of dexmedetomidine for sedation in pediatric patients

STUDY OBJECTIVE: Dexmedetomidine is titrated to achieve sedation in the pediatric and cardiovascular intensive care units (PICU and CVICU). In adults, dexmedetomidine response has been associated with an ADRA2A polymorphism (rs1800544); CC genotype is associated with an increased sedative response c...

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Detalles Bibliográficos
Autores principales: Gallaway, Katherine A., Skaar, Todd C., Biju, Ashwin, Slaven, James, Tillman, Emma M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325491/
https://www.ncbi.nlm.nih.gov/pubmed/35429176
http://dx.doi.org/10.1002/phar.2684