Cargando…

A pilot study of ADRA2A genotype association with doses of dexmedetomidine for sedation in pediatric patients

STUDY OBJECTIVE: Dexmedetomidine is titrated to achieve sedation in the pediatric and cardiovascular intensive care units (PICU and CVICU). In adults, dexmedetomidine response has been associated with an ADRA2A polymorphism (rs1800544); CC genotype is associated with an increased sedative response c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gallaway, Katherine A., Skaar, Todd C., Biju, Ashwin, Slaven, James, Tillman, Emma M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325491/ https://www.ncbi.nlm.nih.gov/pubmed/35429176 http://dx.doi.org/10.1002/phar.2684

Ejemplares similares

Variability of Dosing and Number of Medications Needed to Achieve Adequate Sedation in Mechanically Ventilated Pediatric Intensive Care Patients
por: Tillman, Emma M., et al.
Publicado: (2020)

The effect of alpha-2A adrenergic receptor (ADRA2A) genetic polymorphisms on the depth of sedation of dexmedetomidine: a genetic observational pilot study
por: Choi, Yoon Ji, et al.
Publicado: (2021)

High Dose Dexmedetomidine: Effective as a Sole Agent Sedation for Children Undergoing MRI
por: Ahmed, Sheikh Sohail, et al.
Publicado: (2015)

Corrigendum to “High Dose Dexmedetomidine: Effective as a Sole Agent Sedation for Children Undergoing MRI”
por: Ahmed, Sheikh Sohail, et al.
Publicado: (2015)

Role of dexmedetomidine in pediatric dental sedation
por: Mohite, Vedangi, et al.
Publicado: (2019)

Effects of the Two Doses of Dexmedetomidine on Sedation, Agitation, and Bleeding During Pediatric Adenotonsillectomy
por: Shafa, Amir, et al.
Publicado: (2021)

An Evaluation of Intranasal Sufentanil and Dexmedetomidine for Pediatric Dental Sedation
por: Hitt, James M., et al.
Publicado: (2014)

Effect of ADRA2A gene polymorphisms on the anesthetic and analgesic effects of dexmedetomidine in Chinese Han women with cesarean section
por: Fu, Zhimei, et al.
Publicado: (2020)

The effects of different loading doses of dexmedetomidine on sedation
por: Sim, Jae Hwan, et al.
Publicado: (2014)

Vascular Reactions of the Diving Reflex in Men and Women Carrying Different ADRA1A Genotypes
por: Baranova, Tatyana, et al.
Publicado: (2022)

Differential brain ADRA2A and ADRA2C gene expression and epigenetic regulation in schizophrenia. Effect of antipsychotic drug treatment
por: Brocos-Mosquera, Iria, et al.
Publicado: (2021)

Optimal dose of dexmedetomidine for sedation during spinal anesthesia
por: Ok, Hwoe-Gyeong, et al.
Publicado: (2013)

Effect of dexmedetomidine sedation on swallowing reflex: A pilot study
por: Sanuki, Takuro, et al.
Publicado: (2020)

Dexmedetomidine sedation in ICU
por: Yu, Soo-Bong
Publicado: (2012)

Dexmedetomidine compared with propofol for pediatric sedation during cerebral angiography
por: Peng, Ke, et al.
Publicado: (2014)

Comparison of dexmedetomidine and three different doses of midazolam in preoperative sedation
por: Eren, Gulay, et al.
Publicado: (2011)

Neuroprotective role of dexmedetomidine pretreatment in cerebral ischemia injury via ADRA2A-mediated phosphorylation of ERK1/2 in adult rats
por: Shi, Yanyan, et al.
Publicado: (2018)

The prognostic value of ADRA1 subfamily genes in gastric carcinoma
por: Wang, Tingan, et al.
Publicado: (2019)

Dexmedetomidine for sedation in the medical ICU
por: Venn, RM, et al.
Publicado: (2000)

ADRA2A is involved in neuro-endocrine regulation of bone resorption
por: Mlakar, Vid, et al.
Publicado: (2015)

Dexmedetomidine for sedation following cardiovascular surgery: a two different loading doses
por: Kopel, L, et al.
Publicado: (2005)

Additional sedative drugs to light sedation with dexmedetomidine is risk for delirium
por: Sakuraya, M, et al.
Publicado: (2015)

Clinical significance of expression levels of serum ADRA1A in hysterocarcinoma patients
por: Peng, Lin, et al.
Publicado: (2018)

ADRA2A and IRX1 are putative risk genes for Raynaud’s phenomenon
por: Hartmann, Sylvia, et al.
Publicado: (2023)

Best Evidence-Based Dosing Recommendations for Dexmedetomidine for Premedication and Procedural Sedation in Pediatrics: Outcome of a Risk-Benefit Analysis By the Dutch Pediatric Formulary
por: Freriksen, Jolien J. M., et al.
Publicado: (2022)

Procedural sedation with dexmedetomidine for pediatric endoscopic retrograde cholangiopancreatography guided stone retraction
por: Ko, Byung Ju, et al.
Publicado: (2012)

Pediatric cardiac catheterization procedure with dexmedetomidine sedation: Radiographic airway patency assessment
por: Thimmarayappa, Ashwini, et al.
Publicado: (2015)

Can dexmedetomidine be used as sole maintenance anesthetic agent at standard sedative doses?
por: Bihani, Pooja, et al.
Publicado: (2017)

Effective dose of dexmedetomidine as an adjuvant sedative to peripheral nerve blockade in elderly patients
por: Wang, C., et al.
Publicado: (2018)

Dexmedetomidine for Sedation during Withdrawal of Support
por: O’Hara, Chris, et al.
Publicado: (2015)

Sedation with dexmedetomidine in the intensive care setting
por: Gerlach, Anthony T, et al.
Publicado: (2011)

Sedative and Immunosuppressive Effects of Dexmedetomidine in Transplantation
por: Lee, Chen-Fang, et al.
Publicado: (2021)

The Effectiveness of Low-dose Dexmedetomidine Infusion in Sedative Flexible Bronchoscopy: A Retrospective Analysis
por: Wu, Sheng Hua, et al.
Publicado: (2020)

The Richmond agitation–sedation scale and bispectral index during dexmedetomidine sedation
por: Turkmen, A, et al.
Publicado: (2005)

Dexmedetomidine hydrochloride as a long-term sedative
por: Kunisawa, Takayuki
Publicado: (2011)

Nasal drip of dexmedetomidine for optimal sedation during PICC insertion in pediatric burn care
por: Lu, Yanxu, et al.
Publicado: (2023)

Effective dose of dexmedetomidine to induce adequate sedation in elderly patients under spinal anesthesia
por: Ko, Ki-Ho, et al.
Publicado: (2015)

Intranasal dexmedetomidine and intranasal ketamine association allows shorter induction time for pediatric sedation compared to intranasal dexmedetomidine and oral midazolam
por: Cossovel, Francesca, et al.
Publicado: (2022)

Nephrotoxicity in a Patient With Inadequate Pain Control: Potential Role of Pharmacogenetic Testing for Cytochrome P450 2D6 and Apolipoprotein L1
por: Tillman, Emma M., et al.
Publicado: (2020)

Dexmedetomidine-based sedation for noninvasive ventilation failure
por: Senturk, O, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_4m3jf4t8ojqo4f3dhibbkgimfr