Lipid A Mimetics Based on Unnatural Disaccharide Scaffold as Potent TLR4 Agonists for Prospective Immunotherapeutics and Adjuvants

TLR4 is a key pattern recognition receptor that can sense pathogen‐ and danger‐ associated molecular patterns to activate the downstream signaling pathways which results in the upregulation of transcription factors and expression of interferons and cytokines to mediate protective pro‐inflammatory re...

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Detalles Bibliográficos
Autores principales: Strobl, Sebastian, Hofbauer, Karin, Heine, Holger, Zamyatina, Alla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325513/
https://www.ncbi.nlm.nih.gov/pubmed/35439332
http://dx.doi.org/10.1002/chem.202200547

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325513/
https://www.ncbi.nlm.nih.gov/pubmed/35439332
http://dx.doi.org/10.1002/chem.202200547

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