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HMGB1 Upregulates RAGE to Trigger the Expression of Inflammatory Factors in the Lung Tissue in a Hypoxic Pulmonary Hypertension Rat Model

Hypoxic pulmonary hypertension (HPH), a form of pulmonary hypertension (PH) caused by hypoxia, could cause serious complications and has a high mortality rate, and no clinically effective treatments are currently available. In this study, we established an HPH preclinical model in rats by simulating...

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Detalles Bibliográficos
Autores principales: Li, Wen-Juan, Wen, Zhi-Peng, Xing, Yan, Yang, Jing-Ping, Xu, Xi-Yuan, Wang, Hong-Yan, Zhu, Wen-Yan, Li, Yue-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325572/
https://www.ncbi.nlm.nih.gov/pubmed/35903436
http://dx.doi.org/10.1155/2022/6823743