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A multifaceted strategy to improve recombinant expression and structural characterisation of a Trypanosoma invariant surface protein
Identification of a protein minimal fragment amenable to crystallisation can be time- and labour intensive especially if large amounts are required and the protein has a complex fold and functionally important post-translational modifications. In addition, a lack of homologues and structural informa...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325691/ https://www.ncbi.nlm.nih.gov/pubmed/35882923 http://dx.doi.org/10.1038/s41598-022-16958-x |