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A multifaceted strategy to improve recombinant expression and structural characterisation of a Trypanosoma invariant surface protein

Identification of a protein minimal fragment amenable to crystallisation can be time- and labour intensive especially if large amounts are required and the protein has a complex fold and functionally important post-translational modifications. In addition, a lack of homologues and structural informa...

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Detalles Bibliográficos
Autores principales: Sülzen, Hagen, Votrubova, Jitka, Dhillon, Arun, Zoll, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325691/
https://www.ncbi.nlm.nih.gov/pubmed/35882923
http://dx.doi.org/10.1038/s41598-022-16958-x