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Vav2 is a novel APP-interacting protein that regulates APP protein level

Amyloid precursor protein (APP) is a transmembrane protein that plays critical role in the pathogenesis of Alzheimer's disease (AD). It is also involved in many types of cancers. Increasing evidence has shown that the tyrosine phosphorylation site Y682 in the intracellular tail of APP is crucia...

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Detalles Bibliográficos
Autores principales: Zhang, Youjia, Yang, Xiaxin, Liu, Yongrui, Ge, Liang, Wang, Jiarong, Sun, Xiulian, Wu, Bo, Wang, Junfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325707/
https://www.ncbi.nlm.nih.gov/pubmed/35882892
http://dx.doi.org/10.1038/s41598-022-16883-z