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Shared mechanisms across the major psychiatric and neurodegenerative diseases

Several common psychiatric and neurodegenerative diseases share epidemiologic risk; however, whether they share pathophysiology is unclear and is the focus of our investigation. Using 25 GWAS results and LD score regression, we find eight significant genetic correlations between psychiatric and neur...

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Detalles Bibliográficos
Autores principales: Wingo, Thomas S., Liu, Yue, Gerasimov, Ekaterina S., Vattathil, Selina M., Wynne, Meghan E., Liu, Jiaqi, Lori, Adriana, Faundez, Victor, Bennett, David A., Seyfried, Nicholas T., Levey, Allan I., Wingo, Aliza P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325708/
https://www.ncbi.nlm.nih.gov/pubmed/35882878
http://dx.doi.org/10.1038/s41467-022-31873-5