Theileria annulata histone deacetylase 1 (TaHDAC1) initiates schizont to merozoite stage conversion

A fungal metabolite, FR235222, specifically inhibits a histone deacetylase of the apicomplexan parasite Toxoplasma gondii and TgHDAC3 has emerged as a key factor regulating developmental stage transition in this species. Here, we exploited FR235222 to ask if changes in histone acetylation regulate d...

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Detalles Bibliográficos
Autores principales: Tajeri, Shahin, Momeux, Laurence, Saintpierre, Benjamin, Mfarrej, Sara, Chapple, Alexander, Mourier, Tobias, Shiels, Brian, Ariey, Frédéric, Pain, Arnab, Langsley, Gordon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325746/
https://www.ncbi.nlm.nih.gov/pubmed/35882887
http://dx.doi.org/10.1038/s41598-022-15518-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325746/
https://www.ncbi.nlm.nih.gov/pubmed/35882887
http://dx.doi.org/10.1038/s41598-022-15518-7

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